Anti-ELF4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA058595.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA058595.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Transcriptional activator that binds to DNA sequences containing the consensus... more

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Product information "Anti-ELF4"

Protein function: Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter. Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2. Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 68% and to rat: 68%

Keywords:	Anti-E74-like factor 4, Anti-Myeloid Elf-1-like factor, Anti-ETS-related transcription factor Elf-4
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA058595

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SSRVSSRSAP QGKGSSSWEK PKIQHVGLQP SASLELGPSL DEEIPTTSTM LVSPAEGQVK LTKAVSASSV PSNIHLGVA (ATA-APrEST85340)