Protein function: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]). [The UniProt Consortium]
synthetic peptide. The epitope recognized by A301-771A-T maps to a region between residue 100 and 150 of human eukaryotic translation initiation factor 5 using the numbering given in entry NP_892116.2 (GeneID 1983).