Anti-eIF3B/EIF3S9 (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00659-T 10 µl (5+ slides) -

3 - 9 business days

125.00€
IHC-00659 100 µl (50+ slides) -

3 - 9 business days

470.00€
 
Protein function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3)... more
Product information "Anti-eIF3B/EIF3S9 (IHC)"
Protein function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). [The UniProt Consortium]
Keywords: Anti-hPrt1, Anti-eIF3b, Anti-eIF-3-eta, Anti-eIF3 p110, Anti-eIF3 p116, Anti-Prt1 homolog, Anti-Eukaryotic translation initiation factor 3 subunit B, Anti-Eukaryotic translation initiation factor 3 subunit 9
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00659-T

Properties

Application: IHC, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: The epitope recognized by IHC-00659 maps to a region between residue 100 and 150 of human eukaryotic translation initiation factor 3, subunit B (eukaryotic translation initiation factor 3, subunit 9) using the numbering given in entry NP_003742.2 (GeneID 8662).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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