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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| A303-390A-T | 10 µl (10 µg) | - |
3 - 7 business days* |
165.00€
|
|||
| A303-390A | 100 µl (100 µg) | - |
3 - 7 business days* |
586.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transcriptional regulator (PubMed:8336701, PubMed:8703054, PubMed:15958557).... more
Product information "Anti-EGR1"
Protein function: Transcriptional regulator (PubMed:8336701, PubMed:8703054, PubMed:15958557). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (PubMed:8703054, PubMed:15958557, PubMed:2028256, PubMed:8939742). Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia (PubMed:11100120, PubMed:15958557). Plays a role in the regulation of cell survival, proliferation and cell death (PubMed:15265859, PubMed:15958557). Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor formation (PubMed:15958557). Required for normal progress through mitosis and normal proliferation of hepatocytes after partial hepatectomy (PubMed:15265859). Mediates responses to ischemia and hypoxia, regulates the expression of proteins such as IL1B and CXCL2 that are involved in inflammatory processes and development of tissue damage after ischemia (PubMed:11100120). Regulates biosynthesis of luteinizing hormone (LHB) in the pituitary (PubMed:8703054). [The UniProt Consortium]
| Keywords: | Anti-Egr1, Anti-EGR-1, Anti-Egr-1, Anti-NGFI-A, Anti-Zinc finger protein Krox-24, Anti-Transcription factor Zif268, Anti-Early growth response protein 1, Anti-Nerve growth factor-induced protein A |
| Supplier: | Bethyl Laboratories |
| Supplier-Nr: | A303-390A |
Properties
| Application: | WB, IP |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse (Expected: bovine) |
| Immunogen: | synthetic peptide. The epitope recognized by A303-390A-T maps to a region between residue 1 and 50 of mouse Early Growth Response Protein 1 using the numbering given in entry NP_031939.1 (GeneID 13653). |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K09203 | Matching products |
| UniProt ID : | P08046 | Matching products |
| Gene ID : | GeneID 13653 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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