Anti-EDEM3

Anti-EDEM3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES9649.50 50 µl - -

10 - 15 business days*

173.00€
ELK-ES9649.100 100 µl - -

10 - 15 business days*

290.00€
 
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are... more
Product information "Anti-EDEM3"
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008], Protein function: Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans (PubMed:25092655). May also participate in mannose trimming from all glycoproteins and not just misfolded ones targeted to ERAD (PubMed:34143952). May have alpha 1,2-mannosidase activity. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Endoplasmic reticulum lumen .
Keywords: Anti-EDEM3, Anti-C1orf22, Anti-Alpha-1,2-mannosidase EDEM3, Anti-ER degradation-enhancing alpha-mannosidase-like protein 3, EDEM3 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES9649

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from part region of human protein
MW: 102 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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