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Extracellular matrix protein 1 (ECM1) is a glycoprotein involved in a number of biological processes such as such as bone formation,skin differentiation,cell proliferation,and promotes angiostasis. Pathologically,ECM1 contributes to the formation and metastasis of several types of cancer including breast,thyroid and hepatocellular cancers.(21128013) It inhibits MMP9 proteolytic activity. Protein function: Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. [The UniProt Consortium]
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