Anti-ECD

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA006465.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA006465.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Regulator of p53/TP53 stability and function. Inhibits MDM2- mediated... more

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Product information "Anti-ECD"

Protein function: Regulator of p53/TP53 stability and function. Inhibits MDM2- mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839). The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PubMed:26711270). May play a role in regulation of pre-mRNA splicing (PubMed:24722212). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 64% and to rat: 69%

Keywords:	Anti-ECD, Anti-hSGT1, Anti-Human suppressor of GCR two, Anti-Protein ecdysoneless homolog
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA006465

Properties

Application:	ICC, IHC, WB, ChIP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DEDFECLDSD DDLDFETHEP GEEASLKGTL DNLKSYMAQM DQELAHTCIS KSFTTRNQVE PVSQTTDNNS DEEDSGTGES VMAPVDVDLN LVSNILESYS SQAGLAGPAS NLLQSMGVQL PDNTDHRPTS KP (ATA-APrEST70906)