Protein function: Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. [The UniProt Consortium]
Anti-ESYT1, Anti-E-Syt1, Anti-FAM62A, Anti-Extended synaptotagmin-1, Anti-Membrane-bound C2 domain-containing protein
synthetic peptide. The epitope recognized by A303-361A-T maps to a region between residue 350 and 400 of human Extended Synaptotagmin-like Protein 1 using the numbering given in entry NP_056107.1 (GeneID 23344).