Anti-E Cadherin

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-F44156-0.08ML 80 µl - -

3 - 10 business days*

326.00€
NSJ-F44156-0.4ML 400 µl - -

3 - 10 business days*

702.00€
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. CDH1 is a classical cadherin from the cadherin... more
Product information "Anti-E Cadherin"
In 1X PBS, pH 7.4, with 0.09% sodium azide. CDH1 is a classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. [The UniProt Consortium]
Keywords: Anti-CDH1, Anti-CDHE, E Cadherin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: F44156

Properties

Application: WB, FC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: A portion of amino acids 160-189 from the human protein was used as the immunogen for this E Cadherin antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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