Anti-DUS2L

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES6684.50 50 µl - -

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169.00€
ELK-ES6684.100 100 µl - -

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283.00€
 
dihydrouridine synthase 2(DUS2) Homo sapiens This gene encodes a cytoplasmic protein that... more
Product information "Anti-DUS2L"
dihydrouridine synthase 2(DUS2) Homo sapiens This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012], Protein function: Dihydrouridine synthase. Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:15994936, PubMed:26429968, PubMed:30149704, PubMed:34798057). Negatively regulates the activation of EIF2AK2/PKR (PubMed:18096616). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Cytoplasm . Endoplasmic reticulum . Mainly at the endoplasmic reticulum. .
Keywords: Anti-DUS2, Anti-DUS2L, Anti-hDUS2, Anti-URLC8, Anti-Dihydrouridine synthase 2, Anti-tRNA-dihydrouridine synthase 2-like, Anti-Up-regulated in lung cancer protein 8, Anti-tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, DUS2L rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES6684

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: The antiserum was produced against synthesized peptide derived from human DUS2L. AA range:421-470
MW: 55 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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