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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG63850.100 | 100 µg | - | - |
6 - 14 business days* |
784.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Atypical chemokine receptor that controls chemokine levels and localization via... more
Product information "Anti-Duffy / FY / DARC, N-terminal"
Protein function: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1, TARC and also for the malaria parasites P.vivax and P.knowlesi. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes, when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels. [The UniProt Consortium]
Keywords: | Anti-GpFy, Anti-DARC, Anti-ACKR1, Anti-CD234, Anti-Glycoprotein D, Anti-Fy glycoprotein, Anti-Plasmodium vivax receptor, Anti-Atypical chemokine receptor 1, Anti-Duffy antigen/chemokine receptor |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG63850 |
Properties
Application: | ELISA, FC, IHC (paraffin), WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human |
Immunogen: | HRAELSPSTENSSQLDFED-C |
Format: | Ammonium Sulfate Precipitated |
Database Information
KEGG ID : | K06574 | Matching products |
UniProt ID : | Q16570 | Matching products |
Gene ID | GeneID 2532 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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