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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A300-834A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A300-834A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4... more
Product information "Anti-DTX3L/BBAP"
Protein function: Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4 (H4K91ub1), in response to DNA damage. Protects cells exposed to DNA-damaging agents. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post- translational modifications such as H4 'Lys-20' methylation (H4K20me). Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation. In concert with PARP9, plays a role in PARP1-dependent DNA damage repair. PARP1- dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites. [The UniProt Consortium]
Keywords: | Anti-BBAP, Anti-DTX3L, Anti-Rhysin2, Anti-Rhysin-2, Anti-Protein deltex-3-like, Anti-E3 ubiquitin-protein ligase DTX3L, Anti-B-lymphoma- and BAL-associated protein, Anti-RING-type E3 ubiquitin transferase DTX3L |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A300-834A |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: mouse) |
Immunogen: | synthetic peptide. The epitope recognized by A300-834A-T maps to a region between residue 700 and the C-terminus (residue 740) of human Deltex 3-Like Protein (B-Lymphoma- and BAL-Associated Protein) using the numbering given in entry NP_612144.1 (GeneID 151636). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K06058 | Matching products |
UniProt ID : | Q8TDB6 | Matching products |
Gene ID | GeneID 151636 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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