Anti-DSCR1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F40133-0.08ML	80 µl		-	-	3 - 10 business days*		361.00€
NSJ-F40133-0.4ML	400 µl		-	-	3 - 10 business days*		772.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. DSCR1 (calcipressin 1) interacts with calcineurin A... more

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Product information "Anti-DSCR1"

In 1X PBS, pH 7.4, with 0.09% sodium azide. DSCR1 (calcipressin 1) interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. Thr gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Protein function: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. [The UniProt Consortium]

Keywords:	Anti-RCAN1, Anti-MCIP1, Anti-ADAPT78, Anti-Adapt78, Anti-Calcipressin-1, Anti-Regulator of calcineurin 1, Anti-Down syndrome critical region protein 1, Anti-Myocyte-enriched calcineurin-interacting protein 1, DSCR1 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	F40133

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	A portion of amino acids 75-104 from the human protein was used as the immunogen for this DSCR1 antibody.
Format:	Purified