Anti-Drebrin 1 (DBN1), clone DBN1/3393

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cell cortex, Cell junction, Cell projection, Cytoplasm, Dendrite, Growth cone. Positive Control: kidney and pancreas., PC3 cells. Brain neurons. Also found in the heart, Placenta, Skeletal muscle. Chromosome Location: 5q35.3. Protein Function: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed:20215400). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (PubMed:20215400). Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in memory-related synaptic plasticity in the hippocampus (By similarity) [The Uniprot Consortium]