Anti-DOK1

Item number	Size	Manual	Delivery time	Price
E-AB-10290.20	20 µl	-	7 - 16 business days*	71.00€
E-AB-10290.60	60 µl	-	7 - 16 business days*	143.00€
E-AB-10290.120	120 µl	-	7 - 16 business days*	238.00€
E-AB-10290.200	200 µl	-	7 - 16 business days*	396.00€

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The protein encoded by this gene is part of a signal transduction pathway downstream of receptor... more

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Product information "Anti-DOK1"

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. Protein function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. [The UniProt Consortium]

Keywords:	Anti-pp62, Anti-DOK1, Anti-p62(dok), Anti-Docking protein 1, Anti-Downstream of tyrosine kinase 1, DOK1 Polyclonal Antibody
Supplier:	Elabscience
Supplier-Nr:	E-AB-10290

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant protein of human DOK1
Format:	Purified