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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG46129.50 | 50 µg | - | - |
10 - 15 business days* |
616.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Guanine nucleotide exchange factor (GEF) which specifically activates small... more
Product information "Anti-DOCK8"
Protein function: Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP (PubMed:28028151, PubMed:22461490). During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane (PubMed:28028151). Is involved in NK cell cytotoxicity by controlling polarization of microtubule-organizing center (MTOC), and possibly regulating CCDC88B-mediated lytic granule transport to MTOC during cell killing (PubMed:25762780). [The UniProt Consortium]
| Keywords: | Anti-DOCK8, Anti-Dedicator of cytokinesis protein 8, Anti-Dedicator of cytokinesis protein 8 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG46129 |
Properties
| Application: | IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | A 17 amino acid synthetic peptide within the last 50 amino acids of human DOCK8 |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K21852 | Matching products |
| UniProt ID : | Q8NF50 | Matching products |
| Gene ID : | GeneID 81704 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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