Anti-DOCK7

Anti-DOCK7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB17236.20 20 µl -

9 - 20 business days*

103.00€
 
Protein function: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1... more
Product information "Anti-DOCK7"
Protein function: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton (PubMed:29467281). Has a role in pigmentation. Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal- to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3. [The UniProt Consortium]
Keywords: Anti-DOCK7, Anti-KIAA1771, Anti-Dedicator of cytokinesis protein 7
Supplier: Assay Genie
Supplier-Nr: CAB17236

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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