Anti-DOCK7

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-357A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-357A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1... more

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Product information "Anti-DOCK7"

Protein function: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation. Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3. [The UniProt Consortium]

Keywords:	Anti-DOCK7, Anti-KIAA1771, Anti-Dedicator of cytokinesis protein 7
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-357A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine, dog, horse, rabbit, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, duckbill platypus, white-tufted-ear marmoset, crab-eating macaque, naked mole rat, small-eared galago, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A303-357A-T maps to a region between residue 175 and 225 of human Dedicator of Cytokinesis 7 using the numbering given in entry Q96N67.4 (GeneID 85440).
Format:	Antigen Affinity Purified