Protein function: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42. [The UniProt Consortium]
Anti-ACG, Anti-Zizimin-2, Anti-Dedicator of cytokinesis protein 11, Anti-Activated Cdc42-associated guanine nucleotide exchange factor
synthetic peptide. The epitope recognized by A301-638A-T maps to a region between residue 100 and 150 of human dedicator of cytokinesis 11 using the numbering given in entry NP_653259.3 (GeneID 139818).