Anti-DOC11

Anti-DOC11
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES9581.50 50 µl - -

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169.00€
ELK-ES9581.100 100 µl - -

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283.00€
 
domain:The DHR-2 domain is necessary for the GEF activity.,function:Guanine nucleotide-exchange... more
Product information "Anti-DOC11"
domain:The DHR-2 domain is necessary for the GEF activity.,function:Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DOCK family.,similarity:Contains 1 DHR-1 (CZH-1) domain.,similarity:Contains 1 DHR-2 (CZH-2) domain.,similarity:Contains 1 PH domain.,subunit:Interacts with CDC42., Protein function: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: intracellular,cytosol,
Keywords: Anti-ACG, Anti-Zizimin-2, Anti-Dedicator of cytokinesis protein 11, Anti-Activated Cdc42-associated guanine nucleotide exchange factor, DOC11 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES9581

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from part region of human protein
MW: 228 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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