Anti-Dnmt3a, clone PCRP-DNMT3A-1E2

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3827SAF-100UG 100 µg - -

3 - 10 business days*

810.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. DNMT3A is required for genome-wide de novo... more
Product information "Anti-Dnmt3a, clone PCRP-DNMT3A-1E2"
1 mg/ml in 1X PBS, BSA free, sodium azide free. DNMT3A is required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
Keywords: Anti-MLANA, Anti-Antigen SK29-AA, Anti-Protein Melan-A, Anti-Antigen LB39-AA, Anti-Melanoma antigen recognized by T-cells 1, Dnmt3a Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3827SAF

Properties

Application: IHC (paraffin), WB
Antibody Type: Monoclonal
Clone: PCRP-DNMT3A-1E2
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant full length human protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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