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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| NSJ-F54166-0.05ML | 50 µl | - | - |
3 - 10 business days* |
361.00€
|
||
| NSJ-F54166-0.2ML | 200 µl | - | - |
3 - 10 business days* |
772.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. DnaJ homolog subfamily C member 3 is involved in the... more
Product information "Anti-DNAJC3 (Center Region)"
In 1X PBS, pH 7.4, with 0.09% sodium azide. DnaJ homolog subfamily C member 3 is involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity. Protein function: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity. [The UniProt Consortium]
| Keywords: | Anti-ERdj6, Anti-DNAJC3, Anti-P58IPK, Anti-ER-resident protein ERdj6, Anti-Protein kinase inhibitor p58, Anti-DnaJ homolog subfamily C member 3, Anti-Protein kinase inhibitor of 58 kDa, Anti-Endoplasmic reticulum DNA J domain-containing protein 6, DNAJC3 |
| Supplier: | NSJ Bioreagents |
| Supplier-Nr: | F54166 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | mouse |
| Immunogen: | A portion of amino acids 189-223 from human DNAJC3 |
| Format: | Purified |
Database Information
| KEGG ID : | K09523 | Matching products |
| UniProt ID : | Q13217 | Matching products |
| Gene ID : | GeneID 5611 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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