Anti-DNAJC3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA039336.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA039336.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Involved in the unfolded protein response (UPR) during endoplasmic reticulum... more

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Product information "Anti-DNAJC3"

Protein function: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF- 2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 95%

Keywords:	Anti-ERdj6, Anti-DNAJC3, Anti-P58IPK, Anti-ER-resident protein ERdj6, Anti-Protein kinase inhibitor p58, Anti-DnaJ homolog subfamily C member 3, Anti-Protein kinase inhibitor of 58 kDa, Anti-Endoplasmic reticulum DNA J domain-containing protein 6
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA039336

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: YKISTLYYQL GDHELSLSEV RECLKLDQDH KRCFAHYKQV KKLNKLIESA EELIRDGRYT DATSKYESVM KTEPSIAEYT VR (ATA-APrEST81277)