Anti-DNAJB6

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG41182.100 100 µl - -

6 - 14 business days*

707.00€
 
Protein function: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts... more
Product information "Anti-DNAJB6"
Protein function: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity. [The UniProt Consortium]
Keywords: Anti-MRJ, Anti-HSJ2, Anti-HHDJ1, Anti-HSJ-2, Anti-MSJ-1, Anti-DNAJB6, Anti-Heat shock protein J2, Anti-DnaJ homolog subfamily B member 6
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG41182

Properties

Application: ICC, IF, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant fusion protein corresponding to aa. 177-326 of Human DNAJB6 (NP_490647.1)
MW: 36 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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