Anti-DNAJB6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KC-1085.50	50 µl		-	-	Request delivery time estimate		232.00€
ABS-KC-1085.100	100 µl		-	-	Request delivery time estimate		332.00€

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Protein function: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts... more

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Product information "Anti-DNAJB6"

Protein function: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity. [The UniProt Consortium]

Keywords:	Anti-DnaJ homolog subfamily B member 6, Anti-HHDJ1, Anti-Heat shock protein J2, Anti-HSJ-2, Anti-MRJ, Anti-MSJ-1, DNAJB6 Antibody
Supplier:	Absea
Supplier-Nr:	KC-1085

Properties

Antibody Type:	Monoclonal
Clone:	5D5
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse
Immunogen:	Recombinant human DNAJB6
Format:	Solution

Database Information

KEGG ID :	K09512 \| Matching products
UniProt ID :	O75190 \| Matching products
Gene ID :	GeneID 10049 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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