Anti-DMPK

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA007164.25 25 µl -

3 - 8 business days*

330.00€
ATA-HPA007164.100 100 µl -

3 - 8 business days*

463.00€
 
Protein function: Non-receptor serine/threonine protein kinase which is necessary for the... more
Product information "Anti-DMPK"
Protein function: Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 73% and to rat: 74%
Keywords: Anti-DMK, Anti-DMPK, Anti-DM1PK, Anti-MT-PK, Anti-DM-kinase, EC=2.7.11.1, Anti-DM1 protein kinase, Anti-Myotonin-protein kinase, Anti-Myotonic dystrophy protein kinase
Supplier: Atlas Antibodies
Supplier-Nr: HPA007164

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SDIREGAPLG VHLPFVGYSY SCMALRDSEV PGPTPMELEA EQLLEPHVQA PSLEPSVSPQ DETAEVAVPA AVPAAEAEAE VTLRELQEAL EEEVLTRQSL SREMEAIRTD NQNFASQLRE AEARNRDLEA HVRQLQERME (ATA-APrEST71375)

Database Information

KEGG ID : K08788 | Matching products
UniProt ID : Q09013 | Matching products
Gene ID : GeneID 1760 | Matching products
Protein Atlas Nr. : ENSG00000104936

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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