Anti-DLST (Dihydrolipoyllysine-residue Succinyltransferase Component Of 2-oxoglutarate Dehydrogenase

Anti-DLST (Dihydrolipoyllysine-residue Succinyltransferase Component Of 2-oxoglutarate Dehydrogenase
Item number Size Datasheet Manual SDS Delivery time Quantity Price
D7800-20C.100 100 µl - -

1 - 19 business days

496.00€
 
Alpha-ketoglutarate dehydrogenase complex is a rate-regulating enzyme in the Krebs Cycle in... more
Product information "Anti-DLST (Dihydrolipoyllysine-residue Succinyltransferase Component Of 2-oxoglutarate Dehydrogenase"
Alpha-ketoglutarate dehydrogenase complex is a rate-regulating enzyme in the Krebs Cycle in mitochondria (1). Dihydrolipoamide succinyltransferase (DLST) is a key subunit in this complex (2). Mutations in the DLST gene may be responsible for the familial Alzheimer disease (1). Reduction of DLST increases the generation of reactive oxygen species production suggesting its role in oxidative stress (2). Deficiency of DLST in mice was suggested to cause increased oxidative stress in mitochondria and is involved in the pathogenesis of Alzheimer disease (2). Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight., Immunoprecipitation: 1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
Keywords: EC=2.3.1.61, Anti-OGDC-E2, Anti-2-oxoglutarate dehydrogenase complex component E2, Anti-Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex
Supplier: United States Biological
Supplier-Nr: D7800-20C

Properties

Application: IP, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Monkey, Mouse, Rat
Immunogen: Synthetic peptide corresponding to residues surrounding Val188 of human DLST.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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