Anti-DKC1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA001022.25	25 µl		-		3 - 8 business days*		330.00€
ATA-HPA001022.100	100 µl		-		3 - 8 business days*		463.00€

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Protein function: [Isoform 1]: Catalytic subunit of H/ACA small nucleolar ribonucleoprotein... more

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Product information "Anti-DKC1"

Protein function: [Isoform 1]: Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (PubMed:25219674). This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 (PubMed:25219674). Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Required for ribosome biogenesis and telomere maintenance (PubMed:19179534, PubMed:25219674). Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme (PubMed:19179534). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 86%

Keywords:	Anti-NOLA4, Anti-Dyskerin, Anti-CBF5 homolog, Anti-snoRNP protein DKC1, Anti-Nucleolar protein NAP57, Anti-Nucleolar protein family A member 4, Anti-Nopp140-associated protein of 57 kDa, Anti-H/ACA ribonucleoprotein complex subunit DKC1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA001022

Properties

Application:	ICC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KERKSLPEED VAEIQHAEEF LIKPESKVAK LDTSQWPLLL KNFDKLNVRT THYTPLACGS NPLKREIGDY IRTGFINLDK PSNPSSHEVV AWIRRILRVE KTGHSGTL (ATA-APrEST74149)