Anti-DKC1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-592A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-592A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable... more

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Product information "Anti-DKC1"

Protein function: Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. [The UniProt Consortium]

Keywords:	Anti-DKC1, Anti-NOLA4, Anti-Dyskerin, EC=5.4.99.-, Anti-CBF5 homolog, Anti-snoRNP protein DKC1, Anti-Nucleolar protein NAP57, Anti-Nucleolar protein family A member 4, Anti-Nopp140-associated protein of 57 kDa
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-592A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine, dog, panda, orangutan, gorilla, chimpanzee, white-tufted-ear marmoset, dusky titi monkey, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-592A-T maps to a region between residue 390 and 440 of human dyskeratosis congenita 1 using the numbering given in entry NP_001354.1 (GeneID 1736).
Format:	Antigen Affinity Purified