Anti-DIAPH3

Anti-DIAPH3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG45063.50 50 µl - -

10 - 15 business days*

584.00€
 
Protein function: Actin nucleation and elongation factor required for the assembly of F-actin... more
Product information "Anti-DIAPH3"
Protein function: Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Required for cytokinesis, stress fiber formation and transcriptional activation of the serum response factor. Binds to GTP-bound form of Rho and to profilin: acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Also acts as an actin nucleation and elongation factor in the nucleus by promoting nuclear actin polymerization inside the nucleus to drive serum-dependent SRF-MRTFA activity. [The UniProt Consortium]
Keywords: Anti-DRF3, Anti-DRF3, Anti-DIAP3, Anti-MDia2, Anti-MDia2, Anti-DIAPH3, Anti-Diaphanous-related formin-3, Anti-Diaphanous-related formin-3, Anti-Protein diaphanous homolog 3, Anti-Protein diaphanous homolog 3
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG45063

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: DIAPH3 synthetic peptide corresponding to amino acid residues near the C-terminus of human DIAPH3.This peptide sequence is highly conserved in rat and mouse DIAPH3, and has low homology to other formins
MW: 137 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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