Anti-DHDDS

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA026721.25	25 µl		-		3 - 8 business days*		246.00€
ATA-HPA026721.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: With NUS1, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an... more

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Product information "Anti-DHDDS"

Protein function: With NUS1, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:25066056, PubMed:28842490, PubMed:32817466). Synthesizes long-chain polyprenols, mostly of C95 and C100 chain length (PubMed:32817466). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol (PubMed:21572394). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 91% and to rat: 91%

Keywords:	Anti-CIT, Anti-HDS, Anti-Cis-IPTase, Anti-Cis-isoprenyltransferase, Anti-Epididymis tissue protein Li 189m, Anti-Cis-prenyltransferase subunit hCIT, Anti-Dehydrodolichyl diphosphate synthase complex subunit DHDDS
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA026721

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RSKSEVDGLM DLARQKFSRL MEEKEKLQKH GVCIRVLGDL HLLPLDLQEL IAQAVQATKN YNKCFLNVCF AYTSRHEISN A (ATA-APrEST76691)