Anti-Desmoglein 1 / DSG1, clone 27B2

Anti-Desmoglein 1 / DSG1, clone 27B2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3265SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. Desmoglein 1 (DSG1) is a member of the desmosomal... more
Product information "Anti-Desmoglein 1 / DSG1, clone 27B2"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Desmoglein 1 (DSG1) is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity. Protein function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [The UniProt Consortium]
Keywords: Anti-DG1, Anti-DGI, Anti-DSG1, Anti-CDHF4, Anti-Desmoglein-1, Anti-Cadherin family member 4, Anti-Desmosomal glycoprotein 1, Anti-Pemphigus foliaceus antigen, Desmoglein 1 Antibody / DSG1
Supplier: NSJ Bioreagents
Supplier-Nr: V3265SAF-100UG

Properties

Application: FC, IF, WB, IP
Antibody Type: Monoclonal
Clone: 27B2
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the DSG1 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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