Anti-DEPDC5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA055619.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA055619.100	100 µl		-		7 - 10 business days*		491.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: As a component of the GATOR1 complex functions as an inhibitor of the amino... more

Close menu

Product information "Anti-DEPDC5"

Protein function: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 91%

Keywords:	Anti-GATOR complex protein DEPDC5, Anti-DEP domain-containing protein 5
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA055619

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: YDAQVFRLPG PSRAQCLTTC RSVRERESHS RKSASSCDVS SSPSLPSRTL PTEEVRSQAS DDSSLGKSAN ILMIPHPHLH QYEVSSS (ATA-APrEST78172)