Anti-DDX42

Anti-DDX42
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-354A-T 20 µl (2 blots) -

3 - 9 business days

125.00€
A303-354A-M 100 µl (10 blots) -

3 - 9 business days

290.00€
A303-354A 100 µl (100 µg) -

3 - 9 business days

430.00€
 
Protein function: ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs)... more
Product information "Anti-DDX42"
Protein function: ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm. [The UniProt Consortium]
Keywords: Anti-RHELP, Anti-RNAHP, Anti-DDX42, Anti-SF3b125, EC=3.6.4.13, Anti-DEAD box protein 42, Anti-SF3b DEAD box protein, Anti-RNA helicase-like protein, Anti-RNA helicase-related protein, Anti-ATP-dependent RNA helicase DDX42
Supplier-Nr: A303-354A-T

Properties

Application: WB, IP
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse (Expected: Chicken, Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A303-354A-T maps to a region between residue 888 and 938 of human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 using the numbering given in entry NP_031398.2 (GeneID 11325).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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