Anti-DDX4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41563.50	50 µg		-	-	6 - 14 business days*		551.00€

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Protein function: ATP-dependent RNA helicase required during spermatogenesis (PubMed:10920202,... more

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Product information "Anti-DDX4"

Protein function: ATP-dependent RNA helicase required during spermatogenesis (PubMed:10920202, PubMed:21034600). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping- pong amplification cycle. Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs. [The UniProt Consortium]

Keywords:	Anti-VASA, Anti-DDX4, Anti-Vasa homolog, Anti-DEAD box protein 4, Anti-Probable ATP-dependent RNA helicase DDX4
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41563

Properties

Application:	FC, ICC, IF, IHC (frozen), IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat (Expected: hamster)
Immunogen:	Synthetic peptide corresponding to aa. 253-272 of Human DDX4. (EDEDSIFAHYQTGINFDKYD)
MW:	79 kD
Format:	Antigen Affinity Purified