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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-PACO36598.50 | 50 µg | - |
9 - 20 business days* |
363.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
DDI2 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for... more
Product information "Anti-DDI2"
DDI2 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, WB, IHC applications. DDI2 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane (PubMed:27676298, PubMed:27528193). Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1 (PubMed:27528193). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 (Probable). Required, with DDI1, for cellular survival following replication stress. Together or redudantly with DDI1, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (PubMed:29290612). [The UniProt Consortium]
| Keywords: | Anti-Protein DDI1 homolog 2 |
| Supplier: | Assay Genie |
| Supplier-Nr: | PACO36598 |
Properties
| Application: | ELISA, WB, IHC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Human Protein DDI1 homolog 2 protein (1-211AA) |
Database Information
| KEGG ID : | K11885 | Matching products |
| UniProt ID : | Q5TDH0 | Matching products |
| Gene ID | GeneID 84301 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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