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Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A305-444A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A305-444A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap... more
Product information "Anti-DCPS"
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) to m7GMP (PubMed:22985415). May also play a role in the 5'->3 mRNA decay pathway, m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP (PubMed:14523240). Binds to m7GpppG and strongly to m7GDP. Plays a role in first intron splicing of pre- mRNAs. Inhibits activation-induced cell death. [The UniProt Consortium]
Keywords: | Anti-DCS1, Anti-DCPS, Anti-DCS-1, Anti-HINT-5, Anti-HSPC015, EC=3.6.1.59, Anti-m7GpppX diphosphatase, Anti-Decapping scavenger enzyme, Anti-Histidine triad protein member 5, Anti-Scavenger mRNA-decapping enzyme DcpS |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A305-444A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | synthetic peptide. The epitope recognized by A305-444A-T maps to a region between residue 287 to 337 of human Scavenger mRNA-decapping enzyme DcpS using the numbering given in entry Q96C86.2 (GeneID 28960). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K12584 | Matching products |
UniProt ID : | Q96C86 | Matching products |
Gene ID | GeneID 28960 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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