Anti-Cytokeratin 8, clone C-43

Anti-Cytokeratin 8, clone C-43
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2663SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. Cytokeratin 8 (CK8) belongs to the type II... more
Product information "Anti-Cytokeratin 8, clone C-43"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant) carcinoma of the breast. Protein function: Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. [The UniProt Consortium]
Keywords: Anti-K8, Anti-CK-8, Anti-KRT8, Anti-CYK8, Anti-Keratin-8, Anti-Cytokeratin-8, Anti-Type-II keratin Kb8, Anti-Keratin, type II cytoskeletal 8, Cytokeratin 8 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2663SAF

Properties

Application: FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: C-43
Conjugate: No
Host: Mouse
Species reactivity: human, sheep, rabbit, bovine, swine
Immunogen: Cytoskeletal preparation from HeLa cells
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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