Anti-Cytokeratin 7, clone KRT7/1499R (recombinant antibody)

Anti-Cytokeratin 7, clone KRT7/1499R (recombinant antibody)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7258IHC-7ML 7 ml - -

3 - 10 business days*

752.00€
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*.... more
Product information "Anti-Cytokeratin 7, clone KRT7/1499R (recombinant antibody)"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. Cytokeratin-7 (CK7) is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK7 is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. It is found in simple glandular epithelia, and in transitional epithelium. Epithelial cells of the lung and breast both contain CK7, but some other glandular epithelia, such as those of the colon and prostate, do not. Because the protein is found in both healthy and neoplastic cells, antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas from colonic and prostate cancers, respectively. It is commonly used together with CK20 when making such diagnoses. [Wiki] Protein function: Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). [The UniProt Consortium]
Keywords: Anti-K7, Anti-SCL, Anti-KRT7, Anti-CK-7, Anti-Keratin-7, Anti-Sarcolectin, Anti-Cytokeratin-7, Anti-Type-II keratin Kb7, Anti-Keratin, type II cytoskeletal 7, Recombinant Cytokeratin 7 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V7258IHC

Properties

Application: FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: KRT7/1499R
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Full-length human CK7 protein was used as the immunogen for the recombinant Cytokeratin 7 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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