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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V7128IHC-7ML | 7 ml | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*.... more
Product information "Anti-Cytokeratin 17, clone CTKN17-1"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. Cytokeratin 17 is a type I keratin. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. [Wiki] Protein function: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. [The UniProt Consortium]
Keywords: | Anti-K17, Anti-39.1, Anti-CK-17, Anti-KRT17, Anti-Keratin-17, Anti-Cytokeratin-17, Anti-Keratin, type I cytoskeletal 17, Cytokeratin 17 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V7128IHC |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | CTKN17-1 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant full-length human KRT17 protein was used as the immunogen for the Cytokeratin 17 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K07604 | Matching products |
UniProt ID : | Q04695 | Matching products |
Gene ID | GeneID 3872 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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