Anti-Cytokeratin 15, clone SPM190

Anti-Cytokeratin 15, clone SPM190
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3455SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. Keratins are a family of intermediate filament... more
Product information "Anti-Cytokeratin 15, clone SPM190"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.
Keywords: Anti-K15, Anti-KRTB, Anti-KRT15, Anti-CK-15, Anti-Keratin-15, Anti-Cytokeratin-15, Anti-Keratin, type I cytoskeletal 15, Cytokeratin 15 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3455SAF

Properties

Application: WB, FC, IF, IHC (paraffin), (IF)
Antibody Type: Monoclonal
Clone: SPM190
Conjugate: No
Host: Mouse
Species reactivity: human, rat, bovine
Immunogen: An amino acid sequence from the C-terminal portion of the human protein was used as the immunogen for the Cytokeratin 15 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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