Anti-Cytokeratin 10, clone SPM623

Anti-Cytokeratin 10, clone SPM623
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3310SAF-100UG 100 µg - -

3 - 10 business days

1 mg/ml in 1X PBS, BSA free, sodium azide free. This mAb recognizes a protein of 56.5kDa,... more
Product information "Anti-Cytokeratin 10, clone SPM623"
1 mg/ml in 1X PBS, BSA free, sodium azide free. This mAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Keywords: Anti-K10, Anti-KPP, Anti-CK-10, Anti-KRT10, Anti-Keratin-10, Anti-Cytokeratin-10, Anti-Keratin, type I cytoskeletal 10, Cytokeratin 10 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3310SAF-100UG


Application: FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: SPM623
Conjugate: No
Host: Mouse
Reactivity: Human, Dog, Cat
Immunogen: A cytoskeletal preparation extracted from human ectocervical epithelium was used as the immunogen for the Cytokeratin 10 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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