Anti-CXXC5

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA058148.25 25 µl -

7 - 10 business days*

246.00€
ATA-HPA058148.100 100 µl -

7 - 10 business days*

491.00€
 
Protein function: May indirectly participate in activation of the NF-kappa-B and MAPK pathways.... more
Product information "Anti-CXXC5"
Protein function: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (PubMed:29276034). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: Anti-CF5, Anti-RINF, Anti-CXXC5, Anti-HSPC195, Anti-CXXC-type zinc finger protein 5, Anti-Retinoid-inducible nuclear factor, Anti-Putative MAPK-activating protein PM08, Anti-Putative NF-kappa-B-activating protein 102
Supplier: Atlas Antibodies
Supplier-Nr: HPA058148

Properties

Application: ICC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ASLLANGHDL AAAMAVDKSN PTSKHKSGAV ASLLSKAERA TELAAEGQLT LQQFAQSTEM LKRVVQEHLP L (ATA-APrEST89839)

Database Information

KEGG ID : K22760 | Matching products
UniProt ID : Q7LFL8 | Matching products
Gene ID : GeneID 51523 | Matching products
Protein Atlas Nr. : ENSG00000171604

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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