Anti-CXXC5

Anti-CXXC5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG45876.50 50 µg - -

6 - 14 business days*

518.00€
 
Protein function: May indirectly participate in activation of the NF-kappa-B and MAPK pathways.... more
Product information "Anti-CXXC5"
Protein function: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (PubMed:29276034). [The UniProt Consortium]
Keywords: Anti-CF5, Anti-CF5, Anti-RINF, Anti-RINF, Anti-CXXC5, Anti-HSPC195, Anti-CXXC-type zinc finger protein 5, Anti-CXXC-type zinc finger protein 5, Anti-Retinoid-inducible nuclear factor, Anti-Retinoid-inducible nuclear factor, Anti-Putative MAPK-activating p
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG45876

Properties

Application: FC, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide corresponding to middle region of human CXXC5
MW: 33 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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