Anti-CXorf67

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA004003.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA004003.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Inhibits PRC2/EED-EZH1 and PRC2/EED-EZH2 complex function by inhibiting... more

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Product information "Anti-CXorf67"

Protein function: Inhibits PRC2/EED-EZH1 and PRC2/EED-EZH2 complex function by inhibiting EZH1/EZH2 methyltransferase activity, thereby causing down- regulation of histone H3 trimethylation on 'Lys-27' (H3K27me3) (PubMed:29909548, PubMed:31086175, PubMed:31451685, PubMed:30923826). Probably inhibits methyltransferase activity by limiting the stimulatory effect of cofactors such as AEBP2 and JARID2 (PubMed:30923826). Inhibits H3K27me3 deposition during spermatogenesis and oogenesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 26% and to rat: 27%

Keywords:	Anti-EZH inhibitory protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA004003

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TVSSQASPSG GAALSSSTAG SSAAAATSAA IFITDEASGL PIIAAVLTER HSDRQDCRSP HEVFGCVVPE GGSQAAVGPQ KATGHADEHL AQTKSPGNSR RRKQPCRNQA APAQKPPGRR LFPEPLPPSS PGFRPSSYPC SGAST (ATA-APrEST74453)