Anti-CXCR7 (G-protein Coupled Receptor 159, Chemokine Orphan Receptor 1, G-protein Coupled Receptor

Anti-CXCR7 (G-protein Coupled Receptor 159, Chemokine Orphan Receptor 1, G-protein Coupled Receptor
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C8376-25L.100 100 µg - -

3 - 19 business days*

688.00€
 
CXCR7/RDC1 is a 362aa CXC chemokine receptor involved in a number of pathobiologic processes,... more
Product information "Anti-CXCR7 (G-protein Coupled Receptor 159, Chemokine Orphan Receptor 1, G-protein Coupled Receptor"
CXCR7/RDC1 is a 362aa CXC chemokine receptor involved in a number of pathobiologic processes, including cell growth, survival and adhesion, and tumor growth. It belongs to the G-protein coupled receptor 1 family. Though CXCR7 was previously identified as a receptor for vasoactive intestinal peptide (VIP), it is now considered as an orphan receptor in that its endogenous ligand has not been identified. It is an alternative receptor for CXCL12/SDF1 and ITAC (CXCL11) as well as acts as a co-receptor with CXCR4 for a restricted number of HIV isolates. Reports suggest that CXCR7 may act as a link between inflammation and cancer. This membrane protein is usually expressed in monocytes, basophils, and B-cells while low expression is also seen in CD4+ T-lymphocytes and natural killer cells. Applications: Suitable for use in Flow Cytometry, Western Blot, Neutralization and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 4-6ug/ml, Immunohistochemistry (formalin fixed paraffin embedded): 10ug/ml, Flow Cytometry (Cell surface): 1-10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-Chemokine orphan receptor 1, Anti-G-protein coupled receptor 159, Anti-C-X-C chemokine receptor type 7, Anti-G-protein coupled receptor RDC1 homolog
Supplier: United States Biological
Supplier-Nr: C8376-25L

Properties

Application: FC, IHC, FA (Neutr.), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: bovine, horse, human, monkey, mouse, rat
Immunogen: Synthetic peptide (QHNQWPMGELTC) corresponding to aa106-117 of human CXCR7, NP_064707.1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-CXCR7 (G-protein Coupled Receptor 159, Chemokine Orphan Receptor 1, G-protein Coupled Receptor"
Write a review
or to review a product.
Viewed