Anti-CX3CL1

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Chemokine(C-X3-C motif) ligand 1 is a large cytokine protein. It is said to be the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice). Its gene is mapped to the long arm of chromosome 8. Being the large protein, it has got 373 amino acids. Imai et al.(1997) identified a 7-transmembrane high-affinity receptor(CX3CR1, 601470) for fractalkine and showed that it mediates both the adhesive and migratory functions of fractalkine. Protein function: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. [The UniProt Consortium]