Anti-CSNK2A2

Anti-CSNK2A2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030123.100 100 µl - -

3 - 19 business days*

505.00€
 
Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine:threonine... more
Product information "Anti-CSNK2A2"
Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine:threonine protein kinasethat is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alphaand alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits arecatalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to thealpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteinsimplicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thoughtto influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via thephosphorylation of Akt. Applications: Western Blot: 1:500-1:2000, Flow Cytometry: 1:200-1:400, ELISA: 1:10000, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-CK2A2, Anti-CSNK2A2, EC=2.7.11.1, Anti-CK II alpha', Anti-Casein kinase II subunit alpha'
Supplier: United States Biological
Supplier-Nr: 030123

Properties

Application: ELISA, FC, WB
Antibody Type: Monoclonal
Clone: 13B201
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse
Immunogen: Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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