Anti-COPS2

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA018271.25 25 µl -

7 - 10 business days*

300.00€
ATA-HPA018271.100 100 µl -

7 - 10 business days*

421.00€
 
Protein function: Essential component of the COP9 signalosome complex (CSN), a complex involved... more
Product information "Anti-COPS2"
Protein function: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: Anti-CSN2, Anti-SGN2, Anti-COPS2, Anti-TRIP-15, Anti-Alien homolog, Anti-Signalosome subunit 2, Anti-TR-interacting protein 15, Anti-COP9 signalosome complex subunit 2, Anti-JAB1-containing signalosome subunit 2
Supplier: Atlas Antibodies
Supplier-Nr: HPA018271

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PFIREHIEEL LRNIRTQVLI KLIKPYTRIH IPFISKELNI DVADVESLLV QCILDNTIHG RIDQVNQLLE LDHQKRGGAR YTALDKWTNQ LNSLNQAVVS KLA (ATA-APrEST73774)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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