Anti-Cofilin, clone 1C1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG56973.50	50 µl		-	-	6 - 14 business days*		488.00€

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Protein function: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity.... more

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Product information "Anti-Cofilin, clone 1C1"

Protein function: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration. [The UniProt Consortium]

Keywords:	Anti-CFL, Anti-p18, Anti-CFL1, Anti-Cofilin-1, Anti-18 kDa phosphoprotein, Anti-Cofilin, non-muscle isoform
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56973

Properties

Application:	WB, FC
Antibody Type:	Monoclonal
Clone:	1C1
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant fragment around aa. 1-166 of Human Cofilin
Format:	Purified